The first Angel stepped up and poured his bowl out on earth: Loathsome, stinking sores erupted on all who had taken the mark of the Beast and worshiped its image.
The fifth Angel poured his bowl on the throne of the Beast: Its kingdom fell into sudden eclipse. Mad with pain, men and women bit and chewed their tongues,
The sixth Angel poured his bowl on the great Euphrates River: It dried up to nothing. The dry riverbed became a fine roadbed for the kings from the East.
These are demon spirits performing signs. They're after the kings of the whole world to get them gathered for battle on the Great Day of God, the Sovereign-Strong.
"Keep watch! I come unannounced, like a thief. You're blessed if, awake and dressed, you're ready for me. Too bad if you're found running through the streets, naked and ashamed."
followed by lightning flashes and shouts, thunder crashes and a colossal earthquake--a huge and devastating earthquake, never an earthquake like it since time began.
The Great City split three ways, the cities of the nations toppled to ruin. Great Babylon had to drink the wine of God's raging anger--God remembered to give her the cup!